General Information

  • ID:  hor003544
  • Uniprot ID:  E9G007
  • Protein name:  Periviscerokinin-2
  • Gene name:  NA
  • Organism:  Daphnia pulex (Water flea)
  • Family:  Periviscerokinin family
  • Source:  Animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Daphnia (genus), Daphniidae (family), Anomopoda (infraorder), Cladocera (suborder), Diplostraca (order), Phyllopoda (subclass), Branchiopoda (class), Crustacea (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  HLIPFPRV
  • Length:  8(88-95)
  • Propeptide:  MRIAIIHSLVLVVIYLAYSDAAPPQILKSQSLIPFPRVGRSRSSFIANAVGSARSGGAGNPMMMGSGGNANGKSPNNWMMNNADIKRHLIPFPRVGKRQNLIPFPRVGRAGYYQPGFFPSTDDEEGQASIQQQFALSSEESQASAPSSFLMSGSDILGALNNGRSNSDERTAVFIPRRWMTNSQESEE
  • Signal peptide:  MRIAIIHSLVLVVIYLAYSDA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Myotropic activity
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-E9G007-F1(AlphaFold_DB_ID)

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor003544_AF2.pdbhor003544_ESM.pdb

Physical Information

Mass: 110324 Formula: C48H75N13O9
Absent amino acids: ACDEGKMNQSTWY Common amino acids: P
pI: 10.55 Basic residues: 2
Polar residues: 0 Hydrophobic residues: 4
Hydrophobicity: 55 Boman Index: -272
Half-Life: 3.5 hour Half-Life Yeast: 10 min
Half-Life E.Coli: >10 hour Aliphatic Index 133.75
Instability Index: 4387.5 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  21830762
  • Title:  Genomics, Transcriptomics, and Peptidomics of Daphnia Pulex Neuropeptides and Protein Hormones